Antibiotic-resistant E. coli; photo courtesy of Dr. Graham Beards

Antibiotic use and antibiotic resistance

Antibiotic resistance has grown to critical levels in recent years, with few new drugs in the developmental pipeline. With the World Health Organization warning of a “post-antibiotic” era, there is an urgent need to understand the causes underlying changes in resistance. My research focuses on how antibiotic use affects the prevalence of resistance to the antibiotics used to treat common infections and how statistical models can be used to get better estimates of the prevalence of antibiotic resistance into the hands of health practitioners.

Aedes aegypti mosquito; photo courtesy of Prof. Frank Hadley Collins

Modelling the potential distributions of human disease vectors

Climate change and international travel are allowing disease vectors such as the blacklegged tick (Ixodes scapularis) and the Asian tiger mosquito (Aedes albopictus) to expand into new territory. Lyme disease, once unknown in Canada, is now becoming commonplace. Zika virus has become established in invasive mosquito populations in North America. How far and how fast might these diseases spread? My research employs species distribution modelling to help answer these questions. This research is done in collaboration with Dr. Manisha Kulkarni at the University of Ottawa.